How does Mounjaro compare to Saxenda and Wegovy?
Mounjaro, a newer weight loss injection available in the UK, has shown greater average weight loss than both Saxenda and Wegovy in recent studies. On the highest recommended dose, people using Mounjaro lost up to 22.5% of their body weight over about a year and a half, compared to around 15% with Wegovy and about 8–10% with Saxenda. All three medications help by reducing appetite, but Mounjaro works through two biological pathways, making it more effective for many people. These medicines are only available on prescription and are meant to be used alongside a healthy diet and exercise. While Mounjaro can be an excellent option for significant weight loss, it’s important to consult a healthcare professional to determine the most suitable treatment for your needs.
- Mounjaro can help people lose up to 22.5% of their starting body weight, which is typically more than with Saxenda or Wegovy.
- Wegovy users generally lose around 15% of their body weight, while Saxenda users lose 8–10% on average.
- Mounjaro works by mimicking two appetite-regulating hormones, while Wegovy and Saxenda focus on one.
- All medicines require a prescription and work best with diet and exercise.
- Your doctor can advise which treatment suits you best, as the effectiveness and suitability vary from person to person.
Sources
- BBC News – Mounjaro mechanism of action
- British Heart Foundation – Mounjaro vs Wegovy
- Drugs.com – Weight loss with Wegovy
- Drugs.com – Saxenda weight loss results
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- Kyodo News PR Wire – Weight loss data
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- NovoMedLink – Wegovy efficacy and safety
- NowPatient – Comparison of Saxenda, Wegovy, and Mounjaro
- Numan – Mounjaro results timeline
- ASDA Online Doctor – Mounjaro weekly weight loss
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- UCHealth – How Mounjaro works
- YourPharmacy.uk – Top weight loss injections 2025
- ABC News – Mounjaro and Ozempic study