Does Wegovy interact with other medications?
Yes. Wegovy (semaglutide) can interact with other medicines, particularly those that affect blood sugar, blood pressure, or the stomach’s emptying time. Using it with insulin or some diabetes tablets can increase the risk of low blood sugar, so doses may need adjusting and blood sugars monitored. It should not be combined with other GLP‑1 medicines (e.g., liraglutide or dulaglutide), and caution is needed with some antibiotics that can also lower blood sugar. Because Wegovy slows stomach emptying, it can affect how some oral medicines are absorbed, so a pharmacist or prescriber may advise timing adjustments.
- Combining Wegovy with insulin or certain diabetes tablets can increase low blood sugar risk; dosing and monitoring may need adjusting.
- Avoid using Wegovy alongside other GLP‑1 medicines (such as liraglutide, dulaglutide, or exenatide).
- Some medicines (including certain antibiotics) may further lower blood sugar when taken with Wegovy.
- Wegovy slows stomach emptying, which can affect absorption of some oral medicines; timing changes may help.
- In the UK, always inform a GP, specialist weight‑management service, or pharmacist about all prescriptions, OTC medicines, and supplements before starting Wegovy.
- Seek urgent advice if symptoms of low blood sugar occur (shakiness, sweating, dizziness, confusion), especially when starting or changing doses.