What are the most common side effects of Mounjaro?
The most common side effects of Mounjaro (tirzepatide) are stomach and gut-related, especially nausea, vomiting, diarrhoea, and constipation. These are usually mild to moderate and often improve as the body adapts over a few weeks. Other commonly reported effects include indigestion, stomach pain or discomfort, heartburn, burping, excess wind, dizziness, tiredness, and injection site reactions such as redness or itching.
Some people also experience hair loss and low blood pressure. When Mounjaro is used alongside certain diabetes medicines, low blood sugar can occur. In the UK, side effects can be reported through the Yellow Card scheme, and anyone with severe or persistent symptoms should seek advice from a GP or NHS 111.
- Digestive side effects such as nausea, vomiting, diarrhoea, constipation, indigestion, and stomach pain.
- Injection site reactions including redness, itching, or mild irritation.
- Other common symptoms like dizziness, tiredness, burping, or excess wind.
- Less common but reported: hair loss and low blood pressure.
- Risk of low blood sugar if taken with certain diabetes medicines.