Can Wegovy cause constipation or diarrhoea?
Yes—Wegovy (semaglutide) commonly causes both constipation and diarrhoea, especially when starting treatment or after a dose increase. These bowel changes are usually mild to moderate and tend to improve as the body adjusts over time. UK pharmacy guidance and patient information list constipation and diarrhoea among the most frequent side effects (often affecting more than 1 in 10 people). If symptoms are persistent, severe, or accompanied by warning signs like severe tummy pain, dehydration, or blood in stools, seek advice from a GP, NHS 111, or the prescribing clinician.
- Constipation and diarrhoea are common side effects of Wegovy, particularly early in treatment or after dose increases.
- Symptoms usually settle as the body gets used to the medicine; gradual dose escalation helps limit side effects.
- Staying hydrated, eating smaller meals, and choosing lower-fat foods can help; fibre may ease constipation.
- Contact a healthcare professional if bowel changes are severe, persistent, or cause dehydration.
- Severe or sudden abdominal pain, vomiting, or fever needs urgent assessment (GP, NHS 111, or A&E if necessary).
- People with ongoing symptoms may need tailored advice or adjustments to their treatment plan.