How does Mounjaro affect appetite and cravings?
Mounjaro (tirzepatide) works mainly by regulating appetite signals in the brain, helping people feel full sooner and less hungry overall, which in turn reduces how much they want to eat. Clinical research shows it decreases appetite and food cravings and lowers energy intake, with short-term trials reporting marked reductions in hunger and responsiveness to high-sugar, high-fat foods compared with placebo and some other weight-loss medicines. UK guidance summarises that people on tirzepatide typically experience fewer food cravings alongside greater satiety, which supports eating less as part of a supervised weight-management plan. NHS and UK public-health materials explain that these medicines also slow stomach emptying, helping fullness last longer and stabilising blood sugar, which can further curb cravings.
- Mounjaro helps people feel fuller and less hungry by regulating appetite signals in the brain.
- Studies show it reduces appetite, cravings, and overall calorie intake, including responses to sugary and fatty foods.
- UK guidance notes people commonly report fewer food cravings and increased satiety while on treatment.
- It slows stomach emptying, helping fullness last longer and supporting lower food intake.
- These effects are intended to support, not replace, healthy eating and activity in UK care pathways.