Can you stop Mounjaro abruptly?
Yes, it’s possible to stop Mounjaro (tirzepatide) suddenly and this is not unsafe in itself. However, many UK clinicians advise planning a gradual dose reduction where possible to help appetite and weight changes stay manageable and to minimise discomfort. NICE guidance also sets clear points when stopping should be considered (for example, if less than 5% weight loss is achieved after 6 months on the highest tolerated dose), with the decision made together with a healthcare professional. If you do stop suddenly due to side effects or other reasons, be aware the medicine can remain in the body for several weeks, so effects may fade gradually rather than overnight. Before making changes, speak with a GP, prescribing pharmacist, or weight-management service for individual advice and a support plan.
- You can stop Mounjaro suddenly, but tapering is often recommended to ease the transition and reduce rebound appetite.
- NICE advises reviewing progress and stopping if weight-loss targets aren’t met after 6 months on the highest tolerated dose.
- If you stop abruptly, some effects may wear off over several weeks, as the drug lingers in the system.
- Discuss any plan to stop with a UK healthcare professional to tailor timing, tapering, and follow-up support.
- Services commonly suggest gradual dose reductions to lower the chance of rapid weight regain.