What is the starting dose for Mounjaro?
The starting dose for Mounjaro (tirzepatide) is 2.5mg injected once a week for the first 4 weeks. After this initial period, the dose is usually increased to 5mg once weekly if appropriate. Further increases are typically made in 2.5mg steps every 4 weeks if needed and well tolerated, up to a usual maximum of 15mg once weekly. The 2.5mg dose is specifically an initiation dose to help the body adjust and is not intended for long-term maintenance. Always follow the dosing plan agreed with a healthcare professional in line with UK guidance.
- Starting dose: 2.5mg once weekly for 4 weeks.
- Usual next step: increase to 5mg weekly after the first month if suitable.
- Titration: step up by 2.5mg every ≥4 weeks if needed and tolerated.
- Note: 2.5mg is an initiation (not maintenance) dose.
- Maximum usual maintenance dose: 15mg once weekly.